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Thai study looks at CoronaVac vaccine vs. natural immunity to SARS-COV-2 variants

The authors of this study reported that the WT strain of SARS-CoV-2 was best neutralized by Natural Infection 2020 when compared to CoronaVac and Natural Infection 2021 sera. However, the Alpha variant was best neutralized by Natural Infection 2021 sera, when compared to CoronaVac and Natural Infection 2020 sera.

In the case of the Beta variant, this form of SARS-CoV-2 was best neutralized by Natural Infection 2020 and 2021 sera with higher NAb titer levels. Although the Delta variant was neutralized well by Natural Infection 2020 and 2021 sera, levels of NAb titers were much lower when compared with the Alpha and Beta variants.

In summary, the results of the current study indicate that NAb titers elicited by CoronaVac are much lower when compared to natural infection.

Dr. Priyom Bose, Ph.D. Reviewed by Benedette Cuffari, M.Sc., NEWS MEDICAL
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